Saturday, December 16, 2006

RNA Inheritance

This paper, DNA-mediated non-mendelian inheritance of an epigenetic change in the mouse , is very interesting. As soon as I heard earlier this year of the notion of RNA inheritance (in plants), it occurred to me that the same phenomenon could be what is needed to ennable the mismatch repair and gene conversion that is believed to occur in spermatogenesis to be postponed slightly (until formation of the zygote) so it can be regulated instead by the (female) mate's genome, something I had predicted in January 2004 as being likely on account of how certain very lustful females seem to like lust more than I otherwise could account for, in a way that resonated with me.

It occured to me earlier this year it makes sense that something like what this paper describes would be significant mainly as a way of repairing DNA (I predict that) not only because it would ennable gene conversion in spermatogenesis to be postponed, but also because it would allow damaged DNA on one chromosome to "use" the (RNA made from) DNA of the homologous chromosome to repair itself. This also would for instance explain why sunburn is so much more of a big deal cancer- and pain-wise than the gradual sun exposure that produces suntan. If my hypothesis is correct, genetic damage is only very harmful if it is so intense that both copies of the DNA are likely to be damaged at homologous places. In other words, the signficance to cancer of genetic damage is more proportional to the square (or perhaps third- or fourth-power, thinking strand-wise) of the recent damage.

Here is a good example of the evils of censorship. I had posted the poem explaining my ideas about this gene conversion phenomenon way back in 2004, but because my paranoid parents convinced me I was taking too much of a chance jail-wise of posting such an erotic poem about mere girls, I removed it a week or so later. Well, gee whiz, not only is it not pornography, the idea of it might well be key to understanding cancer among other things. And by having taken it down, now people can't see what a genius I was to predict the phenomenon before scientists did any experiments to make it plausible--not like that's going to help my standing with the scientific community, that I would need, for instance, to be respected enough to get a good job if I ever need to do that. So fuck, I'll post the poem, exactly as I posted it in January 2004, with the same preface I posted it with then. As my relative Maria Weston Chapman once said (regarding Channing's hesitance to speak strongly against the evil of slavery and of women not being allowed to speak in public about such when he felt this might reduce his support among the "respectable" people who put money in his collection plates), "Without courage, no truth, & without truth no other virtue".



[Here's a poem about sex. More particularly, a poem about sex with young females. The stereotype is that parents don't want their young daughters' having sex. However, if my theory is right that girls actually have a greater capacity for sexual pleasure than older females when having sex with a virtuous male, then it would stand to reason that a parent would want her daughter to have sex while she is still young if the daughter is in love with a virtuous male. In particular, mothers, typically being more in tune with their daughters' wants and needs, would probably feel this way. So I try to describe the emotion a typical mother of a pretty female would feel toward her daughter if the daughter actually should soon have sex with a man.

There are several notions I am trying to get at in this poem.

There is the notion that it seems as though girls should have sex largely for their own pleasure. This seems reasonable for at least three reasons. First, for the same reason that sexual pleasure is a most selfish pleasure in males, it is a most unselfish pleasure in females. Yeah, it is a pleasure, and like all pleasures is somewhat selfish, still, it is less selfish than other pleasure. Secondly, moral virtue in males being an especial sexual turn-on to a female when she is young, sexual pleasure is even more innocent in young females than in females generally. Thirdly, when a person is unsure of what constitutes her own view as to what is moral, as young people may be presumed more to be, it rather seems more safe for her compared with adults to be ruled a little more by pleasure than by moral laws. This third reason is the reason I was mainly trying to get at and understand in the poem, my mostly not having thought of its application to young-female sex before.

Also, I am trying to figure out why mothers (and to a lesser agree their daughters) are both turned-on and disturbed by the thought of a male using sex with other young females to increase the sexual pleasure of the daughter. My theories suggest that in young females, sexual lust is unusually contagious, and so girls are very pleased at the thought of other younger females having sex with a decent male if she is having sex with him. Unfortunately, females all too often see this behavior as cruel. They fail to appreciate that the analogy between a female using one male to make another male jealous (thereby increasing the desire of the latter to be depravedly addicting) and a male using other females partly to increase the sexual pleasure of another female for him is a false one. Yes, sure, a just guy if having sex with several females is likely going to more reward the girl he likes most by switching to her most every other time he switches, unabashedly using the other girls to increase the sexual pleasure of this girl, but in him, at least, I can't see how this behavior would encourage him to feel himself less loving of any females he is having sex with. Cruelty would appear irrelevant.

Still, it feels to me like there is a great pleasure that a young female can get from a male very calmly and dispassionately using young girls for her sexual pleasure. Intuitively, this pleasure seems more great than anything I have an explanation for. I think it has something to do with crossover encouraging gene conversion. It as though if enough female unholy lust gets put in a female, genetic inversion happens in such a way that some of the male genetic material in the edge of the converted region (where his genetic material has been less thickly painted with lust and hers has been more thickly painted) will get converted through gene conversion into her DNA. But biology would indicate that such would have to be postponed a generation. I don't really know what is going on, just have a feeling something is going on (involving, perhaps, imprinting, genetic crossover, epigenetic inheritance, etc.) that I have not understood very well yet. But no reason to avoid pleasures just because they aren't understood, right?

As always, I define the word "fuck" so that it implies in addition to copulation merely the absence of any caring responsibility in the subject. Poetical words are screwed-up. Alas, there is no recourse but to a word that also has disgusting connotations. Indeed, both the sodomites and the prudes want there to be no distinction between words suggesting a female wants sex mainly for the sex (suggestive of a loving female) and words suggesting a female wants her ass screwed (suggestive of a guttersnipe). That way sodomizers can make skanky females think they are being smartly loving, and prudes can make others think their selfish tendency to mate for money rather than good sex is just cleanliness. It is necessary, therefore, for me to have decreed what I meant. I prefer this option to unnaturally interrupting my poem by otherwise necessary explanation. That poetical sex words have such unpoetical connotations could be a sign that sex is best discussed only scientifically, as in my book. The reason sex words tend to have bad connotations could be seen as a sign that good people don't tend to force them to have good connotations by using them poetically often. However, girls are not women in general. Girls having sex have had to come to their own understandings about sex quickly, or their love is not really their own love but merely the love a parent or whoever wants them to feel. Only by being very emotional and poetical can a girl understand her sexual nature sufficiently quickly-rational wisdom takes too much time. Thought is slow, too slow for girls wanting to have sex presently. So in this sense emotions and poetry are more appropriate when dealing with girl sex than woman sex. Similarly, good females very much more tend to be willing to have sex without commitment, which tends to imply a short amount of time with the male, when intuition and an absorbing of sensation is paramount, and then a long period of intellectual reflection and deduction. So good females potentially need to be both very emotional and very intellectual at different times, which makes both the poetry of sex and the dry scientifically deductive treatment of sex especially relevant to good females regardless of their tendencies to have sex late or early. Erotic poetry has an important place.]

Sex with Girls
Right now
I want to relax
To dream
Of nude young girls
By the dozens
Catering to all my
Sexual wants
Someone
Wants me to do
The exact same thing
And is frightened
I won't be cruel enough
To do it
The way her secret
Sex thrill
Wants
My penis do it
For her daughter

Cruelty
Is not what people make it out to be
The girls
I want to make love to
I don't want to love
For selfish reasons
I want their
bodies
to be used
For your daughter's
Greater sexual satisfaction
I want them-
sorry, I expect them-
to obey my penis's commands.
A body divided against itself
Can't stand.
Love
Is beautiful
Is good
I want all the girls
Having sex with me
To enjoy it
More than what I know.

I feel like
There is something
I can do
--Something I haven't thought of yet,
That on the face of it
Will give them a sexual pleasure
From copulating with me
Far greater than any I have thought of
Or understood.
Little Girls are young
And easily startled
They don't really know
What is good for themselves
To anything like a degree of certainty.
Still,
They know better
How to experience innocent purely sexual pleasure
Than What love is.
Purely sexual pleasure is the most unselfish pleasure
For a female to want in herself the increase of;
For a little girl, even more so.
I'm not really sure I want girls to copulate for love
I want them mainly to let me fuck them because
they expect by so doing an amount of purely sexual pleasure it doesn't please them to resist.
At night when they masturbate
they obtain (among other things)
an unbiased estimation of the pleasure
sex with me would give.
And then they bias this best unbiased estimator of their pleasure by
taking into account the prior distribution of their pleasure-the
distribution
that gives
the relative probability that a
non-specific man,
chosen at random,
would give an unspecified amount of innocent
purely sexual pleasure
if she should have sex with him.
Combining her best unbiased estimator with
the prior distribution-
Each in proportion to her estimation of its inverse variance-,
she would get a sum;
the sum would tell her for any given level of innocent
sexual pleasure
what the relative chances would be
of obtaining that.

I want girls to have sex with me
because they expect
A level of sexual pleasure
Beyond what they should resist.
Which basically should be the level beyond which they are not pleased to resist.

But a child may be
too scared
to satisfy her innocent pleasant lusts or, Who knows?
Might bark up the wrong tree.

A parent can help
Her daughter get what she sexually wants
By telling her if her sexual desires are innocent, and
by disillusioning her if they are not.

Indeed, I do think sometimes that girls can get much more pleasure in copulating with a man wanting to sexually please them than my theories indicate. I don't really know why, though your explanation whatever it be, is, I think, wrong. Right well it would be to find the answer. Sometimes pleasures have to be thought of and understood to be thoroughly realized. Without understanding comes some error. I want in.

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